Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 11/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032352 | 0.96 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032488 | 0.91 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032533 | 0.91 | CYP11B2 (0.59) | CYP11B2CYP11B1CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL10032669 | 0.90 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13016102 | 0.88 | CYP11B2 (0.67) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032431 | 0.87 | CYP11B2 (0.70) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032182 | 0.87 | CYP11B2 (0.55) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032867 | 0.87 | CYP11B2 (0.57) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL10032486 | 0.86 | CYP11B2 (0.60) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL10032176 | 0.86 | KIF11 (0.57) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060374-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | JNC株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |