SCHEMBL10032924

SCHEMBL10032924

Cc1ccc(-c2ccc(-c3ccc4ccc(-c5c6ccccc6c(-c6ccccc6)c6ccccc56)cc4c3)cc2)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
CYP2A6 P11509 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
CTRC Q99895 1/20 0.39
NPC1 O15118 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032679 0.96 CYP3A4 (0.43) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL10032691 0.95 CYP3A4 (0.44) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL10032923 0.94 CYP3A4 (0.41) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL10032730 0.91 CYP3A4 (0.45) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL10032752 0.90 CYP3A4 (0.40) CYP3A4CYP2A6ALDH1A1HPGDTDP1
SCHEMBL15977779 0.88 CTRC (0.40) CYP3A4CYP2A6MEN1KMT2AALDH1A1
SCHEMBL10032654 0.88 CCR1 (0.43) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL15977627 0.88 CYP3A4 (0.45) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL15161016 0.88 CYP3A4 (0.45) CYP3A4CYP2A6MEN1KMT2AKDM4E
SCHEMBL18174644 0.88 CYP3A4 (0.45) CYP3A4CYP2A6MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed