SCHEMBL10032654

SCHEMBL10032654

Cc1ccc(-c2ccc(-c3ccc4cc(-c5c6ccccc6c(-c6ccccc6)c6ccccc56)ccc4c3)cn2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP11B1 P15538 2/20 0.38
CYP11B2 P19099 2/20 0.38
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
PSMB5 P28074 1/20 0.38
DHODH Q02127 2/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032185 0.92 CYP11B2 (0.42) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032679 0.92 CYP3A4 (0.43) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032784 0.92 CCR1 (0.43) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032730 0.92 CYP3A4 (0.45) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032924 0.88 CYP3A4 (0.42) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032691 0.88 CYP3A4 (0.44) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL13015737 0.87 HSD17B1 (0.45) CYP3A4CYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL10032923 0.87 CYP3A4 (0.41) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL20176785 0.86 CYP1A2 (0.42) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032752 0.86 CYP3A4 (0.40) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed