⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608787 | 1.00 | — | — | |
| SCHEMBL2755679 | 1.00 | — | — | |
| SCHEMBL10005841 | 0.88 | — | — | |
| SCHEMBL24778339 | 0.88 | — | — | |
| SCHEMBL1644540 | 0.88 | — | — | |
| SCHEMBL10005833 | 0.86 | — | — | |
| SCHEMBL10018595 | 0.86 | — | — | |
| SCHEMBL17754504 | 0.85 | — | — | |
| SCHEMBL17758896 | 0.85 | — | — | |
| SCHEMBL16674740 | 0.84 | INPP5A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839624-B2 | Micellar nanoparticles and uses thereof | BIORCHESTRA CO., LTD. (KR) | 2023-12-12 | — | — | US | disclosed |
| US-20230304014-A1 | MIRNA-485 INHIBITOR FOR HUNTINGTON'S DISEASE | BIORCHESTRA CO., LTD. (KR) | 2023-09-28 | — | — | US | disclosed |
| US-20230131083-A1 | USE OF MIRNA-485 INHIBITORS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS (ALS) | BIORCHESTRA CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20160130582-A1 | OLIGONUCLEOTIDE MODULATORS OF B-CELL CLL/LYMPHOMA 11A (BCL11A) AND USES THEREOF | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2016-05-12 | — | — | US | disclosed |
| US-20160108396-A1 | OLIGOMERS TARGETING HEXANUCLEOTIDE REPEAT EXPANSION IN HUMAN C9ORF72 GENE | PFIZER (US) | 2016-04-21 | — | — | US | disclosed |
| US-20150252360-A1 | METHOD FOR SYNTHESISING TEMPLATED MOLECULES | NUEVOLUTION A/S (DK) | 2015-09-10 | — | — | US | disclosed |
| US-20140213632-A1 | HCV Combination Therapy | STELLA APS (DK) | 2014-07-31 | — | — | US | disclosed |
| US-8785617-B2 | Oligomeric compounds for the modulation of HIF-1A expression | SANTARIS PHARMA A/S (DK) | 2014-07-22 | — | — | US | disclosed |
| US-8722583-B2 | Method for selecting a chemical entity from a tagged library | NUEVOLUTION A/S (DK) | 2014-05-13 | — | — | US | disclosed |
| US-20140127159-A1 | HCV Combination Therapy | STELLA APS (DK) | 2014-05-08 | — | — | US | disclosed |
| US-20090318362-A1 | OLIGOMERIC COMPOUNDS FOR THE MODULATION OF SURVIVIN EXPRESSION | HANSEN JENS BO RODE | 2009-12-24 | — | — | US | disclosed |
| US-7622453-B2 | Oligomeric compound of 10-30 nucleobases In length which comprises a target binding domain that is specifically hybridizable to a region ranging from base position No. 1459 (5') to No. 1476 (3') of the human Bcl-2 mRNA; anti-proliferative compounds, pro-apoptotic compounds | SANTARIS PHARMA A/S | 2009-11-24 | — | — | US | disclosed |
| US-20090264353-A1 | Splice Switching Oligomers for TNF Superfamily Receptors and their Use in Treatment of Disease | SANTARIS PHARMA A/S | 2009-10-22 | — | — | US | disclosed |
| US-20090232833-A1 | POLYALKYLENE OXIDES HAVING HINDERED ESTER-BASED BIODEGRADABLE LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2009-09-17 | — | — | US | disclosed |
| US-20090192110-A1 | RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF PIK3CA EXPRESSION | SANTARIS PHARMA A/S | 2009-07-30 | — | — | US | disclosed |
| US-20090011957-A1 | Ligational encoding using building block oligonucleotides | NUEVOLUTION A/S (DK) | 2009-01-08 | — | — | US | disclosed |
| US-20090005335-A1 | COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION | SANTARIS PHARMA A/S (DK) | 2009-01-01 | — | — | US | disclosed |
| US-20080318894-A1 | RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF HER3 | SANTARIS PHARMA A/S (DK) | 2008-12-25 | — | — | US | disclosed |
| US-20080305957-A1 | Method for Obtaining Structural Information Concerning an Encoded Molecule and Method for Selecting Compounds | NUEVOLUTION A/S (DK) | 2008-12-11 | — | — | US | disclosed |
| US-20070191294-A1 | Short interfering rna (sirna) analogues | SANTARIS PHARMA A/S | 2007-08-16 | — | — | US | disclosed |