⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032931 | 1.00 | — | — | |
| SCHEMBL2755679 | 1.00 | — | — | |
| SCHEMBL10005841 | 0.88 | — | — | |
| SCHEMBL24778339 | 0.88 | — | — | |
| SCHEMBL1644540 | 0.88 | — | — | |
| SCHEMBL10005833 | 0.86 | — | — | |
| SCHEMBL10018595 | 0.86 | — | — | |
| SCHEMBL17754504 | 0.85 | — | — | |
| SCHEMBL17758896 | 0.85 | — | — | |
| SCHEMBL16674740 | 0.84 | INPP5A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327524-A1 | GALNAC PHOSPHORAMIDITES, NUCLEIC ACID CONJUGATES THEREOF AND THEIR USE | HOFFMANN-LA ROCHE INC. | 2017-11-16 | — | — | US | disclosed |