SCHEMBL1003305

SCHEMBL1003305

CN(C)CCC[Si](O[Si](C)(C)O[Si](C)(C)C)(C(C)(C)C)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037516 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11210317 0.70 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL13535227 0.70 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL1004580 0.68 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL5157108 0.66 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL3270169 0.65 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL13298074 0.64 DNM1 (0.43) ALDH1A1TSHR
SCHEMBL613736 0.63 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL13171447 0.62 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL14945125 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470894-B2 Hydrolysis resistant organomodified trisiloxane ionic surfactants MOMENTIVE PERFORMANCE MATERIALS (US) 2013-06-25 US disclosed
US-8263669-B2 Hydrolysis resistant organomodified trisiloxane ionic surfactants MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-11 US disclosed
US-20120142535-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. 2012-06-07 US disclosed
US-20110028569-A1 MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. 2011-02-03 US disclosed
US-20110021644-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. 2011-01-27 US disclosed
EP-2237670-A2 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS Momentive Performance Materials Inc. (US) 2010-10-13 EP disclosed
EP-2237673-A2 MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS Momentive Performance Materials Inc. (US) 2010-10-13 EP disclosed
US-20090173912-A1 MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-07-09 US disclosed
US-20090176893-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-07-09 US disclosed
WO-2009085300-A2 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-07-09 WO disclosed
WO-2009085297-A2 MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028569-A1 MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS CHRM1, CHRM2, CD209 ALDH1A1 4311/4885TSHR 29/4885
US-20090176893-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS CHRM2, CHRM1, MSR1 ALDH1A1 3424/4885TSHR 327/4885
US-20120142535-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS CHRM2, CHRM1, MSR1 ALDH1A1 3518/4885TSHR 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.