Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033139 | 0.92 | SIGMAR1 (0.39) | SIGMAR1POLBRAB9ASMN1; SMN2HTR2C | |
| SCHEMBL1709502 | 0.89 | ESR2 (0.35) | SIGMAR1KDM1AGPR88 | |
| SCHEMBL1709427 | 0.89 | ESR2 (0.35) | SIGMAR1KDM1AGPR88 | |
| SCHEMBL1709420 | 0.89 | SIGMAR1 (0.40) | SIGMAR1POLBRAB9ASMN1; SMN2HTR2C | |
| SCHEMBL1709411 | 0.88 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL1709443 | 0.88 | HTR2C (0.34) | SIGMAR1SMN1; SMN2HTR2CHTR2ASLC6A4 | |
| SCHEMBL1709404 | 0.88 | HTR2C (0.34) | SIGMAR1SMN1; SMN2HTR2CHTR2ASLC6A4 | |
| SCHEMBL1709403 | 0.88 | HTR2C (0.34) | SIGMAR1SMN1; SMN2HTR2CHTR2ASLC6A4 | |
| SCHEMBL6917782 | 0.87 | SIGMAR1 (0.45) | SIGMAR1POLBRAB9ASMN1; SMN2SLC6A2 | |
| SCHEMBL1709494 | 0.86 | HTR2C (0.35) | HTR2CHTR2ASLC6A4SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |