Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033139 | 0.95 | SIGMAR1 (0.39) | SIGMAR1KDM1AMAOAMAOBPOLB | |
| SCHEMBL1709491 | 0.90 | KDM1A (0.42) | SIGMAR1KDM1AMAOAMAOBGPR88 | |
| SCHEMBL1709402 | 0.89 | HTR2C (0.34) | SIGMAR1KDM1AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL10033138 | 0.89 | SIGMAR1 (0.42) | SIGMAR1KDM1APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL10032995 | 0.87 | HTR2A (0.34) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL10032988 | 0.86 | KDM1A (0.33) | KDM1AMAOAMAOB | |
| SCHEMBL1709423 | 0.84 | ACHE (0.30) | KDM1AMAOAMAOB | |
| SCHEMBL10032822 | 0.84 | HTR2C (0.33) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL1709450 | 0.84 | HTR2C (0.33) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL10033004 | 0.81 | PSEN1 (0.36) | GPR88SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |