Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673162 | 0.89 | APP (0.55) | APPKCNH2MAPTCYP3A4CA12 | |
| SCHEMBL714294 | 0.87 | APP (0.59) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL437002 | 0.87 | RARB (0.37) | — | |
| SCHEMBL27133978 | 0.87 | APP (0.43) | APPKCNH2MAPTTP53CYP3A4 | |
| SCHEMBL27133977 | 0.87 | APP (0.47) | APPKCNH2MAPTTP53CYP3A4 | |
| SCHEMBL7994765 | 0.81 | APP (0.47) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL12788166 | 0.80 | CYP1A1 (0.39) | — | |
| SCHEMBL14822799 | 0.80 | CYP1A1 (0.39) | — | |
| SCHEMBL10032997 | 0.80 | APP (0.55) | APPKCNH2TP53CA12CA1 | |
| SCHEMBL15441139 | 0.79 | APP (0.46) | APPKCNH2MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032211-A1 | DENDRITIC STRUCTURES BASED ON TETRAARYLMETHANE | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2012-03-15 | — | — | WO | disclosed |