Sugi Predict

Sugi Predict / Compounds / SCHEMBL673162

SCHEMBL673162

SCHEMBL673162

COc1ccc(C#C[Si](C)(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 3/20 0.55
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA7 P43166 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ CA12 O43570 1/20 0.48
▸ CA14 Q9ULX7 1/20 0.48
▸ KCNH2 Q12809 1/20 0.47
▸ ACHE P22303 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ ACACB O00763 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ MCHR1 Q99705 1/20 0.40
▸ TDP1 Q9NUW8 3/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ GRM5 P41594 1/20 0.39
▸ HAO1 Q9UJM8 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714294 0.98 APP (0.59) APPCA1CA2CA7CA9
SCHEMBL7994765 0.91 APP (0.47) APPCA1CA2CA7CA9
SCHEMBL10033154 0.89 APP (0.46) APPCA1CA2CA7CA9
SCHEMBL15441139 0.89 APP (0.46) APPCA1CA2CA7CA9
SCHEMBL15299057 0.87 APP (0.55) APPCA1CA2CA7CA9
SCHEMBL3846192 0.84 GRM5 (0.39) APPALDH1A1ACACBMEN1KMT2A
SCHEMBL711936 0.84 APP (0.48) APPCA1CA2CA9CA12
SCHEMBL1306384 0.83 GABRA1 (0.38) APPALDH1A1MEN1KMT2AGRM5
SCHEMBL22616848 0.83 NQO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL1306505 0.81 APP (0.41) APPALDH1A1MEN1KMT2AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 — — US claimed
US-20220056167-A1 Functionalized Cyclic Polymers and Methods of Preparing Same NATIONAL SCIENCE FOUNDATION 2022-02-24 — — US claimed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 — — WO claimed
CN-111883748-A Method for coating oxide film on surface of lithium ion battery anode powder material 华南理工大学 2020-11-03 — — CN claimed
CN-122036777-A Preparation method of trimethylsilyl compound 华南理工大学 2026-05-15 — — CN disclosed
CN-116444483-B Preparation method of 1, 3-dithiane substituted diene derivative 兰州大学 2025-04-08 — — CN disclosed
US-20240228527-A1 STEREOSELECTIVE C9-C10 BOND FORMATION TRUSTEES OF DARTMOUTH COLLEGE 2024-07-11 — — US disclosed
US-20240228527-A1 STEREOSELECTIVE C9-C10 BOND FORMATION TRUSTEES OF DARTMOUTH COLLEGE 2024-07-11 — — US disclosed
CN-118022844-B Application of two-dimensional conjugated carbon skeleton loaded titanium dioxide composite material in degradation of organic pollutants in sewage 山东大学 2024-06-18 — — CN disclosed
CN-118022844-A Application of two-dimensional conjugated carbon skeleton loaded titanium dioxide composite material in degradation of organic pollutants in sewage 山东大学 2024-05-14 — — CN disclosed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 — — US disclosed
CN-116836104-A Blue light induced method for hydrogen trifluoromethyl of alkynyl compound 湖南大学 2023-10-03 — — CN disclosed
WO-2002060438-A1 SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2002-08-08 — — WO disclosed
US-20020103262-A1 Methods for treating subjects infected with a herpes virus or neisseria gonorrheae KENT STATE UNIVERSITY 2002-08-01 — — US disclosed
US-6402986-B1 LUMINESCENT EUROPIUM CHELATES SHOWING SUPERIOR ABSORPTION AND ENERGY TRANSFER FEATURES; ANTICOUNTERFEITING THE TRUSTEES OF BOSTON UNIVERSITY 2002-06-11 — — US disclosed
US-6350875-B1 COMPOUNDS FOR ELECTRONICS THE UNIVERSITY OF SOUTHERN CALIFORNIA 2002-02-26 — — US disclosed
WO-2002013764-A2 METHODS FOR TREATING SUBJECTS INFECTED WITH A HERPES VIRUS OR NEISSERIA GONORRHEAE NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE (US) 2002-02-21 — — WO disclosed
US-20020016474-A1 Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes WEBER WILLIAM P (US) 2002-02-07 — — US disclosed
WO-2001012576-A1 SYNTHESIS OF CYCLOOCTATETRAENE DERIVATIVES AND THEIR USE AS ELECTRON TRANSPORTERS IN ORGANIC LIGHT EMITTING DIODES THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2001-02-22 — — WO disclosed
WO-2000024742-A1 PYRAZOLOPYRIDINE AS ADENOSINE ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228527-A1 STEREOSELECTIVE C9-C10 BOND FORMATION NR5A1, HSD17B11, ESRRA APP 4225/4885CA1 1282/4885CA2 3657/4885
US-20020016474-A1 Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes SLC18A3, SLC18A2, SLC25A21 APP 4212/4885CA1 4367/4885CA2 2619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.