SCHEMBL437002

SCHEMBL437002

C[Si](C)(C)C#Cc1ccc(C(c2ccc(C#C[Si](C)(C)C)cc2)(c2ccc(C#C[Si](C)(C)C)cc2)c2ccc(C#C[Si](C)(C)C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.37
RARG P13631 1/20 0.37
GABRA1 P14867 4/20 0.33
GABRG2 P18507 4/20 0.33
GABRB3 P28472 4/20 0.33
GABRA5 P31644 4/20 0.33
GABRA3 P34903 4/20 0.33
GABRA2 P47869 4/20 0.33
GABRA6 Q16445 2/20 0.33
KIF11 P52732 1/20 0.33
GABRA4 P48169 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12788166 0.92 CYP1A1 (0.39) RARBRARGGABRA1GABRG2GABRB3
SCHEMBL14822799 0.92 CYP1A1 (0.39) RARBRARGGABRA1GABRG2GABRB3
SCHEMBL10032993 0.90 APP (0.34) RARBRARGGABRA1GABRG2GABRB3
SCHEMBL8960251 0.89 RARB (0.48) RARBRARGGABRA1GABRG2GABRB3
SCHEMBL10033154 0.87 APP (0.46)
SCHEMBL1306384 0.85 GABRA1 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1306505 0.83 APP (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL3348211 0.83 KIF11 (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL8048738 0.83 SLC2A1 (0.39) RARBRARGGABRA1GABRG2GABRB3
SCHEMBL9451551 0.79 GABRA1 (0.33) RARBRARGGABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067779-A1 METALLOPOLYMERS AND ICLICK SYNTHESIS THEREOF UNIVERSITY OF TEXAS SAN ANTONIO (US) 2024-02-29 US disclosed
EP-2276798-B1 METHOD FOR CROSSLINKING BY THERMAL HUISGEN REACTION, CROSSLINKABLE CHROMOPHORIC POLYMERS, AND CROSSLINKED POLYMER SUBSTANCES HAVING STABLE ELECTRO-OPTICAL PROPERTIES CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) 2017-02-01 EP disclosed
US-8410185-B2 Porous polymeric materials for hydrogen storage UCHICAGO ARGONNE, LLC (US) 2013-04-02 US disclosed
US-8410185-B2 Porous polymeric materials for hydrogen storage UCHICAGO ARGONNE, LLC (US) 2013-04-02 US disclosed
US-20120065289-A1 POROUS POLYMERIC MATERIALS FOR HYDROGEN STORAGE UCHICAGO ARGONNE LLC 2012-03-15 US disclosed
US-20120065289-A1 POROUS POLYMERIC MATERIALS FOR HYDROGEN STORAGE UCHICAGO ARGONNE LLC 2012-03-15 US disclosed
US-8076382-B2 Porous polymeric materials for hydrogen storage UCHICAGO ARGONNE, LLC (US) 2011-12-13 US disclosed
US-8076382-B2 Porous polymeric materials for hydrogen storage UCHICAGO ARGONNE, LLC (US) 2011-12-13 US disclosed
WO-2009138643-A1 METHOD FOR CROSSLINKING BY THERMAL HUISGEN REACTION, CROSSLINKABLE CHROMOPHORIC POLYMERS, AND CROSSLINKED POLYMER SUBSTANCES HAVING STABLE ELECTRO-OPTICAL PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2009-11-19 WO disclosed
US-20090023828-A1 Porous Polymeric materials for Hydrogen storage UCHICAGO ARGONNE LLC 2009-01-22 US disclosed
US-20090023828-A1 Porous Polymeric materials for Hydrogen storage UCHICAGO ARGONNE LLC 2009-01-22 US disclosed