Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | MPL | P40238 | 7/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14843891 | 0.79 | MKNK1 (0.49) | MKNK1MKNK2MPLKDRABL1 | |
| SCHEMBL30611577 | 0.77 | MEN1 (0.56) | MKNK1MKNK2MPL | |
| SCHEMBL4666187 | 0.77 | RAD52 (0.59) | MKNK1MKNK2MPLKDR | |
| SCHEMBL23867504 | 0.76 | RAB9A (0.46) | MKNK1MKNK2 | |
| SCHEMBL27606911 | 0.76 | MKNK1 (0.47) | MKNK1MKNK2MPLKDR | |
| SCHEMBL30062475 | 0.76 | MEN1 (0.67) | — | |
| SCHEMBL1323687 | 0.76 | MAPT (0.53) | MKNK1MPLKDR | |
| SCHEMBL4630887 | 0.74 | GSK3A (0.53) | MKNK1MKNK2KDR | |
| SCHEMBL29501363 | 0.73 | TNNI3K (0.51) | MKNK1MKNK2 | |
| SCHEMBL147860 | 0.73 | MKNK1 (0.44) | MKNK1MKNK2MPLKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008527-A1 | PYRIMIDINE COMPOUND AND PEST-CONTROL USAGE THEREFOR | 住友化学株式会社 (JP) | 2012-01-19 | — | — | WO | disclosed |