Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA4 | P22748 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134165 | 0.84 | CA2 (0.60) | CA2CA4CA9CA1ADCY5 | |
| SCHEMBL1673251 | 0.79 | EGFR (0.70) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL17297723 | 0.76 | ADCY5 (0.74) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL983769 | 0.76 | ADORA2A (0.68) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL6045746 | 0.75 | ADCY5 (0.74) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL6045717 | 0.74 | ADCY5 (0.75) | ADCY5EGFRALDH1A1ADORA2APRKACA | |
| SCHEMBL6045556 | 0.74 | ADCY5 (0.75) | ADCY5EGFRALDH1A1ADORA2APRKACA | |
| SCHEMBL17165347 | 0.73 | EGFR (0.66) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL17293996 | 0.73 | ADORA2A (0.62) | ADCY5EGFRALDH1A1ADORA2AADORA1 | |
| SCHEMBL8594401 | 0.73 | EGFR (0.53) | CA2CA4CA9CA1ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | ADK, PRKCH, DMPK | CA2 866/4885CA4 2510/4885CA9 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.