Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL495711 | 0.95 | HTT (0.36) | PTPN1HTTMAPTHDAC6GAA | |
| SCHEMBL13703597 | 0.85 | HTT (0.39) | PTPN1HTTPOLBAPEX1TDP1 | |
| SCHEMBL20709694 | 0.84 | HTT (0.42) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL495657 | 0.83 | THRB (0.42) | PTPN1HTTPOLBAPEX1TDP1 | |
| SCHEMBL19600617 | 0.82 | HTT (0.41) | PTPN1HTTPOLBAPEX1TDP1 | |
| SCHEMBL25767943 | 0.82 | HTT (0.41) | PTPN1HTTPOLBAPEX1TDP1 | |
| SCHEMBL9106590 | 0.80 | HTT (0.44) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL16674100 | 0.80 | HTT (0.44) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL17721435 | 0.80 | HTT (0.44) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL14426393 | 0.80 | HTT (0.44) | HTTPOLBAPEX1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |