Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 5/20 | 0.44 |
| ▸ | NMT2 | O60551 | 4/20 | 0.44 |
| ▸ | MAFG | O15525 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303008 | 0.95 | CNR1 (0.54) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13311812 | 0.81 | TDP1 (0.56) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13311852 | 0.81 | TDP1 (0.55) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29869498 | 0.80 | FOLH1 (0.57) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13311889 | 0.80 | TDP1 (0.53) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL10044328 | 0.80 | TDP1 (0.72) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13432796 | 0.80 | TDP1 (0.54) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL14524270 | 0.80 | TDP1 (0.54) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13311792 | 0.80 | TDP1 (0.54) | TDP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL14524231 | 0.80 | TDP1 (0.54) | TDP1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021923-A1 | METHODS AND SYSTEMS TO DIAGNOSE A CONDITION IN AN INDIVIDUAL | NATIONAL SCIENCE FOUNDATION | 2012-01-26 | — | — | US | disclosed |