Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928558 | 0.82 | TDP1 (0.75) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL22769248 | 0.82 | FOLH1 (0.65) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL17244682 | 0.82 | FOLH1 (0.65) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL17931798 | 0.82 | FOLH1 (0.46) | FOLH1TDP1CASP3CASP1CASP2 | |
| Biotin SCHEMBL565572 | 0.81 | TDP1 (0.72) | FOLH1TDP1CAPN1PLGPRSS1 | |
| Biotin SCHEMBL27757189 | 0.81 | TDP1 (0.72) | FOLH1TDP1CAPN1PLGPRSS1 | |
| SCHEMBL12303008 | 0.81 | CNR1 (0.54) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL10044328 | 0.81 | TDP1 (0.72) | FOLH1TDP1CAPN1PLGPRSS1 | |
| SCHEMBL10033418 | 0.80 | TDP1 (0.51) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL16458328 | 0.80 | FOLH1 (0.62) | FOLH1TDP1CASP3CASP1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11789029-B2 | Temporal traumatic brain injury biomarkers and methods of use thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220268788-A1 | TEMPORAL TRAUMATIC BRAIN INJURY BIOMARKERS AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2022-08-25 | — | — | US | disclosed |