Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085454 | 1.00 | MMP2 (0.53) | MMP2CNR1CNR2GRIN1GRIN2A | |
| SCHEMBL12085636 | 0.91 | CNR1 (0.60) | CNR1CNR2GRIN1GRIN2ACHRNB2 | |
| SCHEMBL10033846 | 0.85 | GRIN1 (0.61) | MMP2GRIN1GRIN2AGNAI3GNAO1 | |
| SCHEMBL12085474 | 0.85 | GRIN1 (0.61) | MMP2GRIN1GRIN2AGNAI3GNAO1 | |
| SCHEMBL20803506 | 0.84 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL12951413 | 0.83 | HDAC3 (0.60) | CNR1GRIN1GRIN2ACHRNB2CHRNB4 | |
| SCHEMBL24179776 | 0.83 | GNAI3 (0.69) | MMP2GRIN1GRIN2AGNAI3GNAO1 | |
| SCHEMBL12085475 | 0.83 | GNAI3 (0.69) | MMP2GRIN1GRIN2AGNAI3GNAO1 | |
| SCHEMBL10033848 | 0.83 | GNAI3 (0.69) | MMP2GRIN1GRIN2AGNAI3GNAO1 | |
| SCHEMBL17749476 | 0.83 | CNR1 (0.67) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |