Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899554 | 0.90 | MAOB (0.57) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL17899557 | 0.85 | NFE2L2 (0.77) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL25842383 | 0.84 | MAOB (0.55) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL25842368 | 0.80 | NFE2L2 (0.68) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL17899577 | 0.80 | KMT2A (0.64) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL17899539 | 0.80 | NFE2L2 (0.56) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL30884869 | 0.78 | NFE2L2 (0.73) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL27003029 | 0.78 | NFE2L2 (0.73) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL29205210 | 0.78 | NFE2L2 (0.73) | NFE2L2MAOBALDH1A1MAPTPOLB | |
| SCHEMBL17899497 | 0.78 | ACHE (0.61) | NFE2L2MAOBALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157474-A1 | Methods of Identifying and Using General or Alternative Splicing Inhibitors | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-06-21 | — | — | US | disclosed |