Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034262 | 0.82 | LTA4H (0.47) | ALDH1A1L3MBTL1KDM4ECHRNB2CHRNB4 | |
| SCHEMBL10034261 | 0.82 | LTA4H (0.47) | ALDH1A1L3MBTL1KDM4ECHRNB2CHRNB4 | |
| SCHEMBL10066574 | 0.80 | CYP3A4 (0.41) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL11111613 | 0.77 | LTA4H (0.53) | CYP3A4CA2L3MBTL1MAPTTDP1 | |
| SCHEMBL11027301 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CA2LMNAL3MBTL1 | |
| SCHEMBL1356320 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL1357035 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL10022711 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL13191758 | 0.75 | LTA4H (0.40) | ALDH1A1CYP3A4L3MBTL1MAPTKDM4E | |
| SCHEMBL4913490 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120048377-A1 | PHOTOSENSITIVE OPTOELECTRONIC DEVICES COMPRISING POLYCYCLIC AROMATIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120048377-A1 | PHOTOSENSITIVE OPTOELECTRONIC DEVICES COMPRISING POLYCYCLIC AROMATIC COMPOUNDS | TYR, PAH, DDT | ALDH1A1 342/4885CYP3A4 321/4885CA2 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.