Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 16/20 | 0.31 |
| ▸ | GBA1 | P04062 | 10/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034554 | 1.00 | QPCT (0.32) | QPCTGBA2GBA1HRH3 | |
| SCHEMBL15217039 | 1.00 | QPCT (0.32) | QPCTGBA2GBA1HRH3 | |
| SCHEMBL15217037 | 0.84 | QPCT (0.34) | QPCTHRH3 | |
| SCHEMBL15217038 | 0.84 | QPCT (0.34) | QPCTHRH3 | |
| SCHEMBL3103755 | 0.82 | GNAO1 (0.40) | GBA2GBA1 | |
| SCHEMBL23921639 | 0.80 | GNAO1 (0.42) | GBA2GBA1 | |
| SCHEMBL3106220 | 0.80 | GNAO1 (0.42) | GBA2GBA1 | |
| SCHEMBL3106518 | 0.80 | TAAR1 (0.38) | GBA2GBA1 | |
| SCHEMBL10034550 | 0.79 | QPCT (0.35) | QPCTHRH3 | |
| SCHEMBL15108634 | 0.79 | QPCT (0.35) | QPCTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033144-A1 | PYRAZOLOQUINOLINE COMPOUND | アステラス製薬株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |