Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 16/20 | 0.31 |
| ▸ | GBA1 | P04062 | 10/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034555 | 1.00 | QPCT (0.32) | QPCTGBA2GBA1HRH3 | |
| SCHEMBL10034554 | 1.00 | QPCT (0.32) | QPCTGBA2GBA1HRH3 | |
| SCHEMBL15217037 | 0.84 | QPCT (0.34) | QPCTHRH3 | |
| SCHEMBL15217038 | 0.84 | QPCT (0.34) | QPCTHRH3 | |
| SCHEMBL3103755 | 0.82 | GNAO1 (0.40) | GBA2GBA1 | |
| SCHEMBL23921639 | 0.80 | GNAO1 (0.42) | GBA2GBA1 | |
| SCHEMBL3106220 | 0.80 | GNAO1 (0.42) | GBA2GBA1 | |
| SCHEMBL3106518 | 0.80 | TAAR1 (0.38) | GBA2GBA1 | |
| SCHEMBL10034550 | 0.79 | QPCT (0.35) | QPCTHRH3 | |
| SCHEMBL15108634 | 0.79 | QPCT (0.35) | QPCTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615089-B1 | Pyrazoloquinoline compounds | ASTELLAS PHARMA INC (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-8822448-B2 | Pyrazoloquinoline compound | ASTELLAS PHARMA INC. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8822448-B2 | Pyrazoloquinoline compound | ASTELLAS PHARMA INC. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20130225553-A1 | PYRAZOLOQUINOLINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225553-A1 | PYRAZOLOQUINOLINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225553-A1 | PYRAZOLOQUINOLINE COMPOUND | PDE9A, PDE5A, PDE2A | QPCT 1757/4885GBA2 398/4885GBA1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.