SCHEMBL10034853

SCHEMBL10034853

Cc1ccccc1-c1nc(-c2ccccc2C)nc(-c2ccccc2O)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.61
SMN1; SMN2 Q16637 5/20 0.58
ALDH1A1 P00352 5/20 0.58
KMT2A Q03164 5/20 0.56
HSD17B10 Q99714 5/20 0.54
TSHR P16473 4/20 0.53
ALOX15 P16050 2/20 0.53
ADORA2A P29274 2/20 0.53
ADORA3 P0DMS8 1/20 0.53
ADORA2B P29275 1/20 0.53
ADORA1 P30542 1/20 0.53
MAPT P10636 8/20 0.49
NPSR1 Q6W5P4 5/20 0.49
MEN1 O00255 4/20 0.49
KDM4E B2RXH2 4/20 0.49
HTT P42858 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 5/20 0.49
NFKB1 P19838 3/20 0.49
NFKB2 Q00653 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10439544 1.00 MAPK1 (0.61) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL12202811 0.91 TSHR (0.68) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL195530 0.87 SMN1; SMN2 (0.71) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL29502789 0.87 SMN1; SMN2 (0.71) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL11810775 0.87 HSP90AA1 (0.55) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL13299337 0.87 KMT2A (0.49) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL14112069 0.85 ALDH1A1 (0.76) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL1245326 0.85 HSD17B10 (0.50) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL19558500 0.83 KMT2A (0.55) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10
SCHEMBL29990554 0.83 KMT2A (0.55) MAPK1SMN1; SMN2ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147931-B2 Cellulose-film modifier, cellulose composition, and optical cellulose film, polarizing plate-protecting film, polarizing plate, and liquid crystal display device, produced by using the same FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-20090046225-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20090029073-A1 CELLULOSE-FILM MODIFIER, CELLULOSE COMPOSITION, AND OPTICAL CELLULOSE FILM, POLARIZING PLATE-PROTECTING FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE, PRODUCED BY USING THE SAME FUJIFILM CORPORATION (JP) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029073-A1 CELLULOSE-FILM MODIFIER, CELLULOSE COMPOSITION, AND OPTICAL CELLULOSE FILM, POLARIZING PLATE-PROTECTING FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE, PRODUCED BY USING THE SAME C1QBP, C1R, C1S MAPK1 1966/4885SMN1; SMN2 4171/4885ALDH1A1 3603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.