Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 9/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004289 | 0.85 | CD40 (0.40) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL14004288 | 0.85 | CD40 (0.40) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL14004569 | 0.83 | CD40 (0.41) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL14004632 | 0.83 | PRMT1 (0.37) | MAPK8MAPK9ALDH1A1KDM4EENPP1 | |
| SCHEMBL14004571 | 0.80 | CD40 (0.41) | ALDH1A1KDM4EENPP1MAPTMEN1 | |
| SCHEMBL10034956 | 0.79 | ALDH1A1 (0.40) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL10035085 | 0.79 | ALDH1A1 (0.40) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL10034997 | 0.79 | ALDH1A1 (0.40) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL10030510 | 0.78 | CCNA2 (0.37) | MAPK8MAPK9CCNA2CDK2CCNA1 | |
| SCHEMBL14004572 | 0.78 | CD40 (0.40) | ALDH1A1KDM4EENPP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418256-B1 | Acid dyes | CLARIANT FINANCE BV LTD (VG) | 2013-03-27 | — | — | EP | disclosed |
| EP-2418256-A1 | Acid dyes | Clariant International Ltd. (CH) | 2012-02-15 | — | — | EP | disclosed |
| WO-2012013301-A1 | ACID DYES | CLARIANT INTERNATIONAL LTD (CH) | 2012-02-02 | — | — | WO | disclosed |