Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034884 | 0.78 | MAPK8 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL10030593 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL10034997 | 0.71 | ALDH1A1 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL10035085 | 0.71 | ALDH1A1 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL10034956 | 0.71 | ALDH1A1 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL14004494 | 0.71 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL14004500 | 0.71 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL14004289 | 0.70 | CD40 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL14004288 | 0.70 | CD40 (0.40) | CCNA2CDK2CCNA1ALDH1A1KDM4E | |
| SCHEMBL13848275 | 0.68 | ALPL (0.39) | CCNA2CDK2CCNA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487922-B1 | AZO DYES | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2012-02-08 | — | — | EP | disclosed |