Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653745 | 0.89 | MAPT (0.34) | ALDH1A1MAPTKDM4ENR2F2HTT | |
| SCHEMBL2747608 | 0.88 | CDK8 (0.32) | MAPTKDM4EHTTCDK8ACVR1 | |
| SCHEMBL28662642 | 0.88 | MAPT (0.33) | ALDH1A1MAPTKDM4ENR2F2HTT | |
| SCHEMBL23061315 | 0.84 | ALDH1A1 (0.31) | ALDH1A1MAPTKDM4ENR2F2HTT | |
| SCHEMBL10035233 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4ENR2F2HTT | |
| SCHEMBL19912833 | 0.84 | KDM4E (0.35) | ALDH1A1MAPTKDM4ENR2F2HTT | |
| SCHEMBL10035229 | 0.82 | KDM4E (0.31) | MAPTKDM4ENR2F2HTTSMN1; SMN2 | |
| SCHEMBL19099426 | 0.81 | LMNA (0.32) | MAPTKDM4ESMN1; SMN2LMNANR3C1 | |
| SCHEMBL10035237 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HTTSMN1; SMN2LMNAACLY | |
| SCHEMBL29790388 | 0.81 | LMNA (0.32) | MAPTKDM4ESMN1; SMN2LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178695-B2 | Applying to unwanted plants or weeds; controlling broadleaf plants | BAYER CROPSCIENCE AG (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20080254990-A1 | 4-(3-Aminobenzoyl)-1,3-dimethylpyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080254990-A1 | 4-(3-Aminobenzoyl)-1,3-dimethylpyrazoles and their use as herbicides | DDT, TH, ABAT | ALDH1A1 135/4885MAPT 4271/4885KDM4E 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.