Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076985 | 0.86 | CYP2D6 (0.37) | MEN1KMT2AGAAKDM4CSMN1; SMN2 | |
| SCHEMBL17632320 | 0.78 | DPP7 (0.40) | MEN1KMT2AGAAKDM4EMAPK1 | |
| SCHEMBL10141101 | 0.74 | CYP2D6 (0.50) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL4352303 | 0.73 | MEN1 (0.43) | MEN1KMT2AGAAKDM4EMAPK1 | |
| SCHEMBL19468466 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL19468487 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL19468495 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL19468525 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL19468486 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A | |
| SCHEMBL19468518 | 0.72 | CYP2D6 (0.48) | MEN1KMT2AKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | US | disclosed |
| WO-2011005609-A2 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | SLC10A2, KCNN3, KCNN2 | MEN1 1222/4885KMT2A 1714/4885GAA 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.