Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035353 | 0.98 | CYP3A4 (0.62) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035327 | 0.98 | CYP3A4 (0.62) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13401011 | 0.96 | SMN1; SMN2 (0.62) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035354 | 0.93 | CYP2D6 (0.70) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035358 | 0.90 | SMN1; SMN2 (0.69) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035351 | 0.88 | SMN1; SMN2 (0.74) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035342 | 0.88 | SMN1; SMN2 (0.74) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10035357 | 0.83 | OXTR (0.64) | CYP19A1CYP3A4CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5161072 | 0.83 | SMN1; SMN2 (0.66) | CYP19A1SMN1; SMN2HPGDHRH1HRH3 | |
| SCHEMBL17223083 | 0.83 | CYP2A6 (0.54) | CYP19A1CYP3A4SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101771-B2 | Triazole derivative, and light-emitting element, light-emitting device, and electronic device using triazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8101771-B2 | Triazole derivative, and light-emitting element, light-emitting device, and electronic device using triazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |