SCHEMBL1003560

SCHEMBL1003560

N[C@@H](Cc1ccc(OC(=O)[C@@H](N)Cc2ccccc2)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.69
PTGS1 P23219 2/20 0.69
ALPI P09923 1/20 0.69
PKM P14618 1/20 0.69
XIAP P98170 1/20 0.69
PTPN1 P18031 2/20 0.55
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
PPARG P37231 6/20 0.48
PPARA Q07869 5/20 0.48
TPH1 P17752 1/20 0.48
GRB2 P62993 1/20 0.48
SLC15A1 P46059 1/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL5699042 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL5608077 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Ammonia Solution, Strong SCHEMBL4780834 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Serine SCHEMBL9073599 0.94 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Cysteine SCHEMBL3496036 0.93 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL5159825 0.91 SLC7A5 (0.56) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL27373982 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1449126 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL7780318 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL10978818 0.89 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024149-A1 PREDICTIVE MARKERS OF IBD Société des Produits Nestlé S.A. (CH) 2018-01-25 US claimed
US-20150293023-A1 SYSTEMS AND METHODS FOR MEASURING TRANSLATION OF TARGET PROTEINS IN CELLS ANIMA CELL METROLOGY, INC. 2015-10-15 US claimed
US-20120183957-A1 SYSTEMS AND METHODS FOR MEASURING TRANSLATION OF TARGET PROTEINS IN CELLS ANIMA CELL METROLOGY, INC. (US) 2012-07-19 US claimed
EP-2255005-A2 USE OF SYNTHETIC SCAFFOLDS FOR THE PRODUCTION OF BIOSYNTHETIC PATHWAY PRODUCTS The Regents of the University of California (US) 2010-12-01 EP claimed
WO-2009108774-A2 USE OF SYNTHETIC SCAFFOLDS FOR THE PRODUCTION OF BIOSYNTHETIC PATHWAY PRODUCTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-09-03 WO claimed
EP-1828243-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS Gastrotech Pharma A/S (DK) 2007-09-05 EP claimed
CN-1283657-C Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities STAGO DIAGNOSTICA (FR) 2006-11-08 CN claimed
WO-2006058539-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS GASTROTECH PHARMA A/S (DK) 2006-06-08 WO claimed
CN-1524087-A Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities 2004-08-25 CN claimed
US-5759811-A Mutant human hedgehog gene THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-06-02 US claimed
EP-0010830-A2 Dehydropeptides Research Corporation (US) 1980-05-14 EP claimed
JP-2053723-A None JP disclosed
EP-4363438-A1 SYMMETRIC PROTEINS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2024-05-08 EP disclosed
US-20240018505-A1 ENZYMATIC MONOCYCLIZATION OF ACYCLIC MONOTERPENOIDS UNIVESITAET STUTTGART (DE) 2024-01-18 US disclosed
US-20230416704-A1 LACTONASE AND STABILIZED MUTANTS THEREOF FOR TREATING FUNGAL INFECTIONS IN PLANTS MIGAL GALILEE RESEARCH INSTITUTE LTD. (IL) 2023-12-28 US disclosed
EP-0035384-B1 DEOXYNUCLEOTIDE LINKERS TO BE ATTACHED TO A CLONED DNA CODING SEQUENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-06-10 EP disclosed
EP-0133550-A2 Process for producing arphamenine in high yield MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1985-02-27 EP disclosed
US-4461619-A Method of predicting biological activity of compounds by nucleic acid models MEDICAL COLLEGE OF GEORGIA RESEARCH INST. (US) 1984-07-24 US disclosed
US-4371614-A E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan AJINOMOTO CO., INC. (JP) 1983-02-01 US disclosed
US-3982999-A LEUKEMIA KHARASCH JEROME A 1976-09-28 US disclosed