Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4780834

N.N[C@@H](Cc1ccc(OC(=O)[C@@H](N)Cc2ccccc2)cc1)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.67
ALPI P09923 1/20 0.67
PKM P14618 1/20 0.67
PTGS1 P23219 1/20 0.67
XIAP P98170 1/20 0.67
PTPN1 P18031 2/20 0.54
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
TPH1 P17752 2/20 0.49
PPARG P37231 6/20 0.47
PPARA Q07869 5/20 0.47
GRB2 P62993 1/20 0.47
SLC15A1 P46059 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL5699042 0.98 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1003560 0.98 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL5608077 0.98 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Serine SCHEMBL9073599 0.93 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Cysteine SCHEMBL3496036 0.92 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL5159825 0.89 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL27373982 0.89 ALPI (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1449126 0.89 ALPI (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL7780318 0.89 ALPI (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL10978818 0.88 SLC7A5 (0.73) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569036-B2 Immobilized TAL biocatalyst for production of para-hydroxycinnamic acid E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-29 US disclosed
US-20080032371-A1 Immobilized TAL biocatalyst for production of para-hydroxycinnamic acid DUPONT US HOLDING, LLC 2008-02-07 US disclosed
US-20080014619-A1 Method of production of para-hydroxycinnamic acid E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-17 US disclosed
WO-2008008182-A2 METHOD OF PRODUCTION OF PARA-HYDROXYCINNAMIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-17 WO disclosed
WO-2008008179-A2 IMMOBILIZED TAL BIOCATALYST FOR PRODUCTION OF PARA-HYDROXYCINNAMIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-17 WO disclosed