Phenylalanine

Phenylalanine

SCHEMBL5699042

N[C@@H](Cc1ccc(OC(=O)[C@@H](N)Cc2ccccc2)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.69
PTGS1 P23219 2/20 0.69
ALPI P09923 1/20 0.69
PKM P14618 1/20 0.69
XIAP P98170 1/20 0.69
PTPN1 P18031 2/20 0.55
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
PPARG P37231 6/20 0.48
PPARA Q07869 5/20 0.48
TPH1 P17752 1/20 0.48
GRB2 P62993 1/20 0.48
SLC15A1 P46059 1/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL5608077 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1003560 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Ammonia Solution, Strong SCHEMBL4780834 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Serine SCHEMBL9073599 0.94 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Cysteine SCHEMBL3496036 0.93 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL5159825 0.91 SLC7A5 (0.56) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL27373982 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1449126 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL7780318 0.90 ALPI (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL10978818 0.89 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152235-A1 IMPROVED BIOMOLECULE DETECTION USING SURFACE-ENHANCED RAMAN SPECTROSCOPY NOSTICS B.V. (NL) 2023-05-18 US disclosed
EP-1689249-A1 DIETARY NON-ESSENTIAL AMINO ACID TYROSINE REGULATES THE BODY WEIGHT OF ANIMALS THROUGH REGULATING THE ANIMAL APPETITE OR FOOD INTAKE Hill's Pet Nutrition Inc. (US) 2006-08-16 EP disclosed
WO-2005055738-A1 DIETARY NON-ESSENTIAL AMINO ACID TYROSINE REGULATES THE BODY WEIGHT OF ANIMALS THROUGH REGULATING THE ANIMAL APPETITE OR FOOD INTAKE HILL'S PET NUTRITION, INC. (US) 2005-06-23 WO disclosed