Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25453564 | 0.89 | CXCR4 (0.39) | CXCR4CHRM5CHRM3RAD52HSD17B10 | |
| SCHEMBL13185218 | 0.88 | RAD52 (0.50) | CXCR4CHRM5CHRM3RAD52HSD17B10 | |
| SCHEMBL28984365 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21730543 | 0.84 | MEN1 (0.43) | CXCR4CHRM5CHRM3RAD52HSD17B10 | |
| SCHEMBL8258583 | 0.84 | CARM1 (0.48) | MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL18286784 | 0.84 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL12309176 | 0.82 | HRH3 (0.52) | MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL18568453 | 0.82 | HRH3 (0.52) | MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL26398697 | 0.81 | ANPEP (0.45) | CXCR4CHRM5CHRM3RAD52HSD17B10 | |
| SCHEMBL7757512 | 0.81 | CXCR4 (0.40) | CXCR4CHRM5CHRM3RAD52HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103448-A1 | ACID GAS ABSORBENT, METHOD FOR REMOVING ACID GAS, AND ACID GAS REMOVAL APPARATUS | KABUSHIKI KAISHA TOSHIBA (JP) | 2026-04-16 | — | — | US | disclosed |
| EP-4725587-A1 | ACID GAS ABSORBENT, METHOD FOR REMOVING ACID GAS, AND ACID GAS REMOVAL APPARATUS | Kabushiki Kaisha Toshiba (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-20230399303-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | UNIV YALE (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399303-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | UNIV YALE (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | YALE UNIVERSITY (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190276425-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2019-09-12 | — | — | US | disclosed |
| US-10336721-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | YALE UNIVERSITY (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180179176-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2018-06-28 | — | — | US | disclosed |
| US-8058275-B2 | Diazabenzo[de] anthracen-3-one compounds and methods for inhibiting PARP | EISAI INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-8058275-B2 | Diazabenzo[de] anthracen-3-one compounds and methods for inhibiting PARP | EISAI INC. (US) | 2011-11-15 | — | — | US | disclosed |
| EP-2319847-A2 | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting PARP | Eisai Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20110092478-A1 | DIAZABENZO[DE] ANTHRACEN-3-ONE COMPOUNDS AND METHODS FOR INHIBITING PARP | EISAI INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110092478-A1 | DIAZABENZO[DE] ANTHRACEN-3-ONE COMPOUNDS AND METHODS FOR INHIBITING PARP | EISAI INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-7820668-B2 | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting PARP | EISAI INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820668-B2 | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting PARP | EISAI INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7498405-B2 | Halogen-substituted thienyl compounds | GENESOFT PHARMACEUTICALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-20090028815-A1 | Diazabenzo[De]anthracen-3-one Compounds and Methods for Inhibiting Parp | MGI GP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090028815-A1 | Diazabenzo[De]anthracen-3-one Compounds and Methods for Inhibiting Parp | MGI GP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | MIF, MMP12, CSF1R | CXCR4 181/4885CHRM5 4331/4885CHRM3 4163/4885 |
| US-20260103448-A1 | ACID GAS ABSORBENT, METHOD FOR REMOVING ACID GAS, AND ACID GAS REMOVAL APPARATUS | SLC9A2, SLCO2A1, SLCO2B1 | CXCR4 2893/4885CHRM5 109/4885CHRM3 154/4885 |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | CXCR4 153/4885CHRM5 1946/4885CHRM3 2895/4885 |
| US-10336721-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | MIF, MMP12, CSF1R | CXCR4 181/4885CHRM5 4331/4885CHRM3 4163/4885 |
| US-20180179176-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | MIF, MMP12, CSF1R | CXCR4 181/4885CHRM5 4331/4885CHRM3 4163/4885 |
| US-20090028815-A1 | Diazabenzo[De]anthracen-3-one Compounds and Methods for Inhibiting Parp | PARP1, PARP2, PARP3 | CXCR4 3184/4885CHRM5 4857/4885CHRM3 4472/4885 |
| US-20190276425-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | MIF, MMP12, CSF1R | CXCR4 181/4885CHRM5 4331/4885CHRM3 4163/4885 |
| US-20230399303-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | CXCR4 481/4885CHRM5 3765/4885CHRM3 4005/4885 |
| US-20110092478-A1 | DIAZABENZO[DE] ANTHRACEN-3-ONE COMPOUNDS AND METHODS FOR INHIBITING PARP | PARP1, PARP2, PARP3 | CXCR4 3184/4885CHRM5 4857/4885CHRM3 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.