Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419852 | 0.87 | HDAC6 (0.57) | HDAC1HDAC6PYGMCHEK1NT5E | |
| SCHEMBL380666 | 0.79 | — | — | |
| SCHEMBL18051426 | 0.79 | HDAC1 (0.39) | HDAC1HDAC6IDO1PYGMACHE | |
| SCHEMBL27462334 | 0.78 | HDAC1 (0.50) | HDAC1HDAC6NPC1ALDH1A1GAA | |
| SCHEMBL80142 | 0.77 | HDAC1 (0.48) | HDAC1HDAC6NISCHRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL3824245 | 0.77 | HDAC6 (0.48) | HDAC1HDAC6GAAIDO1PYGM | |
| SCHEMBL198093 | 0.76 | CNR1 (0.49) | HDAC1HDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9302892 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1260031 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6PYGMCHEK1NT5E | |
| SCHEMBL9188746 | 0.76 | HDAC1 (0.53) | HDAC1HDAC6MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793455-A | A kind of ring iridium (III) metal complex and its preparation method and application | 广东医科大学 | 2018-03-13 | — | — | CN | claimed |
| CN-107573273-A | A kind of preparation method of three substitution, 3 cyanopyrrole analog derivatives | 浙江大学 | 2018-01-12 | — | — | CN | claimed |
| JP-1268791-A | — | — | None | — | — | JP | disclosed |
| CN-119947691-A | Composition comprising a photochemical ultraviolet absorber precursor and a compound for increasing the rate of photochemical conversion thereof | 罗卡福拉达有限公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-3280707-B1 | BICYCLIC QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-12-20 | — | — | EP | disclosed |
| CN-114656654-B | Modified lignin self-repairing conductive hydrogel and preparation method and application thereof | 江苏理工学院 | 2023-07-11 | — | — | CN | disclosed |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| CN-109970708-A | Cannibinoid receptor modulators | 艾尼纳制药公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-103492369-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2019-03-29 | — | — | CN | disclosed |
| US-4906758-A | Preparation of pyrroles from dialkoxytetrahydrofurans | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |
| JP-H01268791-A | COMPOSITION FOR INHIBITION OF CORROSION IN FUEL SYSTEM, AND METHOD FOR USE AND PREPARATION THEREOF | PETROLITE CORP | 1989-10-26 | — | — | JP | disclosed |
| EP-0303206-A2 | Process for the preparation of pyrroles | BASF Aktiengesellschaft (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0140322-B1 | POLYMER CATALYST TRANSDUCERS AND USE THEREOF IN TEST KITS FOR ANALYTICAL METHODS | MILES INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0125415-B1 | PROCESS FOR THE PRODUCTION OF PYRROLES | BASF Aktiengesellschaft (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4560769-A | CATALYTIC CYCLIZATION OF AMMONIA OR AMINE WITH BUT-2-ENE-1,4-DIOL | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4560534-A | Polymer catalyst transducers | MILES LABORATORIES, INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0140322-A2 | Polymer catalyst transducers and use thereof in test kits for analytical methods | MILES INC. (US) | 1985-05-08 | — | — | EP | disclosed |
| EP-0125415-A1 | Process for the production of pyrroles | BASF Aktiengesellschaft (DE) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | HDAC1 3783/4885HDAC6 1847/4885NISCH 3757/4885 |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | HDAC1 3783/4885HDAC6 1847/4885NISCH 3757/4885 |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | HDAC1 3783/4885HDAC6 1847/4885NISCH 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.