Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419852 | 0.87 | HDAC6 (0.57) | HDAC1HDAC6 | |
| SCHEMBL25438695 | 0.81 | NOTUM (0.47) | HDAC1HDAC6 | |
| SCHEMBL380666 | 0.79 | — | — | |
| SCHEMBL28691661 | 0.79 | HDAC1 (0.35) | HDAC1HDAC6SMN1; SMN2POLBMAPT | |
| SCHEMBL27462334 | 0.78 | HDAC1 (0.50) | HDAC1HDAC6ALDH1A1GAAGFER | |
| SCHEMBL80142 | 0.77 | HDAC1 (0.48) | HDAC1HDAC6SMN1; SMN2POLBMAPT | |
| Hydrochloric Acid SCHEMBL3824245 | 0.77 | HDAC6 (0.48) | HDAC1HDAC6GAAGFER | |
| SCHEMBL1260031 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6GSK3AGSK3B | |
| SCHEMBL198093 | 0.76 | CNR1 (0.49) | HDAC1HDAC6SMN1; SMN2POLBMAPT | |
| SCHEMBL10035779 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391752-A1 | PYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED USES | CHULALONGKORN UNIVERSITY (TH) | 2023-12-07 | — | — | US | disclosed |
| CN-105958011-B | Nonaqueous electrolyte secondary battery and positive electrode sheet for same | 日东电工株式会社 | 2020-07-03 | — | — | CN | disclosed |
| CN-105524046-B | The method for preparing azole compounds | 武田药品工业株式会社 | 2019-03-29 | — | — | CN | disclosed |
| CN-106565582-B | Five substituted pyrrole compounds and preparation method thereof | 浙江大学 | 2019-02-19 | — | — | CN | disclosed |
| CN-108779123-A | Fused tetracyclic compound, its composition and purposes | 泰博生物科技有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108129374-A | The method for preparing azole compounds | 武田药品工业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-107709301-A | Pyrazole derivative or pharmacologically acceptable salt thereof | 橘生药品工业株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-106565582-A | Penta-substituted pyrrole compound and preparation method thereof | 浙江大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-102655222-B | Light-emitting component | 株式会社半导体能源研究所 | 2016-08-24 | — | — | CN | disclosed |
| CN-104418787-A | 1-(4-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-5296497-A | 3,4-dehydropiperidine derivatives having psychotropic activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-03-22 | — | — | US | disclosed |
| EP-0398413-A1 | \"3,4-dehydropiperidine derivatives having psychotropic activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-11-22 | — | — | EP | disclosed |
| CN-1036565-A | DISUBSTITUTED PYRROLES | BAYER AG (DE) | 1989-10-25 | — | — | CN | disclosed |
| EP-0289070-A1 | Tertiary arylethyl amine derivatives having opiate-antagonistic activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391752-A1 | PYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED USES | GLS2, PYGL, CPS1 | HDAC1 362/4885HDAC6 380/4885SMN1; SMN2 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.