SCHEMBL10035781

SCHEMBL10035781

Cc1ccc(-c2nnc(-c3ccc(C(C)(C)C)cc3)o2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.66
RAB9A P51151 11/20 0.66
KDM4E B2RXH2 10/20 0.66
SMN1; SMN2 Q16637 6/20 0.63
HPGD P15428 3/20 0.63
NFKB1 P19838 2/20 0.63
NFKB2 Q00653 2/20 0.63
RELA Q04206 2/20 0.63
POLB P06746 1/20 0.63
S1PR1 P21453 1/20 0.59
TSHR P16473 2/20 0.58
KMT2A Q03164 2/20 0.58
ALDH1A1 P00352 6/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MAPT P10636 5/20 0.51
NPSR1 Q6W5P4 2/20 0.51
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10330362 0.98 NPC1 (0.64) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL17991405 0.98 NPC1 (0.64) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL12309408 0.95 NPC1 (0.60) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL3293191 0.92 NPC1 (0.75) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL2623780 0.92 NPC1 (0.75) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL12354770 0.90 NPC1 (0.66) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL12309409 0.90 NPC1 (0.63) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL1104799 0.90 NPC1 (0.72) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL6296907 0.90 NPC1 (0.72) NPC1RAB9AKDM4ESMN1; SMN2HPGD
SCHEMBL12427246 0.86 NPC1 (0.68) NPC1RAB9AKDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9598450-B2 Emissive compounds for organic light-emitting diodes NITTO DENKO CORPORATION (JP) 2017-03-21 US disclosed
US-9065055-B2 Method for preparing doped organic semiconductor materials and formulation utilized therein NOVALED AG (DE) 2015-06-23 US disclosed
US-9065055-B2 Method for preparing doped organic semiconductor materials and formulation utilized therein NOVALED AG (DE) 2015-06-23 US disclosed
EP-2008318-B1 METHOD FOR PREPARING DOPED ORGANIC SEMICONDUCTOR MATERIALS NOVALED AG (DE) 2013-02-13 EP disclosed
US-20120261650-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-10-18 US disclosed
US-8264140-B2 Organic electroluminescence element and display device FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8264140-B2 Organic electroluminescence element and display device FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8102113-B2 Quinoxaline-containing compounds and polymers thereof FUJI XEROX CO., LTD. (JP) 2012-01-24 US disclosed
US-8102113-B2 Quinoxaline-containing compounds and polymers thereof FUJI XEROX CO., LTD. (JP) 2012-01-24 US disclosed
US-7977864-B2 Method and materials for patterning of an amorphous, non-polymeric, organic matrix with electrically active material disposed therein SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-07-12 US disclosed
US-20080069980-A1 METHOD AND MATERIALS FOR PATTERNING OF AN AMORPHOUS, NON-POLYMERIC, ORGANIC MATRIX WITH ELECTRICALLY ACTIVE MATERIAL DISPOSED THEREIN 3M INNOVATIVE PROPERTIES COMPANY 2008-03-20 US disclosed
US-20080007166-A1 METHOD AND MATERIALS FOR PATTERNING OF AN AMORPHOUS, NON-POLYMERIC, ORGANIC MATRIX WITH ELECTRICALLY ACTIVE MATERIAL DISPOSED THEREIN 3M INNOVATIVE PROPERTIES COMPANY 2008-01-10 US disclosed
US-20080007166-A1 METHOD AND MATERIALS FOR PATTERNING OF AN AMORPHOUS, NON-POLYMERIC, ORGANIC MATRIX WITH ELECTRICALLY ACTIVE MATERIAL DISPOSED THEREIN 3M INNOVATIVE PROPERTIES COMPANY 2008-01-10 US disclosed
US-7276322-B2 Transfer layer of amorphous, non-polymeric, organic matrix with a light emitting material disposed in the matrix is coated on a donor substrate; patterning using laser thermal transfer or thermal head transfer to produce electroluminescent device 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-02 US disclosed
US-7276322-B2 Transfer layer of amorphous, non-polymeric, organic matrix with a light emitting material disposed in the matrix is coated on a donor substrate; patterning using laser thermal transfer or thermal head transfer to produce electroluminescent device 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-02 US disclosed
WO-2007107356-A1 METHOD FOR PREPARING DOPED ORGANIC SEMICONDUCTOR MATERIALS AND FORMULATION UTILIZED THEREIN NOVALED AG (DE) 2007-09-27 WO disclosed
US-20070080634-A1 THERMAL TRANSFER OF LIGHT-EMITTING DENDRIMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-04-12 US disclosed
US-20070080634-A1 THERMAL TRANSFER OF LIGHT-EMITTING DENDRIMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-04-12 US disclosed
US-20070003783-A1 Quinoline copolymer and organic electroluminescent device employing same HITACHI CHEMICAL CO LTD (JP) 2007-01-04 US disclosed
US-20070003783-A1 Quinoline copolymer and organic electroluminescent device employing same HITACHI CHEMICAL CO LTD (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120261650-A1 ORGANIC ELECTROLUMINESCENT DEVICE EBPL, PAICS, CCNL2 NPC1 4836/4885RAB9A 2931/4885KDM4E 2331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.