Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.75 |
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623780 | 1.00 | NPC1 (0.75) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL6296907 | 0.98 | NPC1 (0.72) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL1104799 | 0.98 | NPC1 (0.72) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL460873 | 0.94 | NPC1 (0.68) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL12427246 | 0.94 | NPC1 (0.68) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL10035781 | 0.92 | NPC1 (0.66) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL2839508 | 0.92 | S1PR1 (0.69) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL25408258 | 0.90 | NPC1 (0.70) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL74782 | 0.90 | S1PR1 (0.67) | NPC1RAB9AKDM4ES1PR1NR1H4 | |
| SCHEMBL46191 | 0.90 | NPC1 (0.64) | NPC1RAB9AKDM4ES1PR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611818-B2 | Photosensitive resin composition, photosensitive element, resist pattern forming method and process for manufacturing printed circuit board | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2009-11-03 | — | — | US | claimed |
| US-20240300970-A1 | LIGHT-EMITTING DEVICE AND DISPLAY DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2024-09-12 | — | — | US | disclosed |
| CN-108084109-A | Synthesis method of 2, 5-disubstituted-1, 3, 4-oxadiazole | 南京工业大学 | 2018-05-29 | — | — | CN | disclosed |
| US-7723114-B1 | Methods and systems for detection of radionuclides | CLEMSON UNIVERSITY (US) | 2010-05-25 | — | — | US | disclosed |
| US-7611818-B2 | Photosensitive resin composition, photosensitive element, resist pattern forming method and process for manufacturing printed circuit board | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20070077514-A1 | Photosensitive resin composition, photosensitive element, resist pattern forming method and process for manufacturing printed circuit board | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1032850-B1 | SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS | MINNESOTA MINING & MFG (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-1183554-A1 | IN-SITU RADIOACTIVITY DETECTION | 3M Innovative Properties Company (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000077545-A1 | IN-SITU RADIOACTIVITY DETECTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300970-A1 | LIGHT-EMITTING DEVICE AND DISPLAY DEVICE | MAOA, TYR, ALDH1A2 | NPC1 4631/4885RAB9A 3692/4885KDM4E 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.