Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | GFER | P55789 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.69 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17264101 | 0.90 | MAPT (0.59) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL17264097 | 0.85 | MAPT (0.53) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL8236442 | 0.82 | MAPT (0.55) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL6151538 | 0.82 | MAPT (1.00) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL56547 | 0.82 | MAPT (1.00) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL6414948 | 0.82 | MAPT (1.00) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL156523 | 0.81 | MAPT (0.68) | MAPTALDH1A1GFERKDM4EGAA | |
| SCHEMBL156422 | 0.81 | ALDH1A1 (0.68) | MAPTALDH1A1GFERKDM4EGAA | |
| Hydrochloric Acid SCHEMBL3271552 | 0.80 | MAPT (0.96) | MAPTALDH1A1GFERKDM4EGAA | |
| Hydrochloric Acid SCHEMBL4707631 | 0.80 | MAPT (0.96) | MAPTALDH1A1GFERKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |