Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813611 | 0.84 | MAPT (0.75) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31203067 | 0.84 | MAPT (0.75) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1595672 | 0.84 | MAPT (0.65) | NPSR1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL3023182 | 0.83 | ALDH1A1 (0.54) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1594377 | 0.83 | MAPT (0.54) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5254187 | 0.81 | HTT (0.49) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15696780 | 0.80 | ALDH1A1 (0.51) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10035933 | 0.78 | EHMT2 (0.49) | ALDH1A1CYP3A4GAA | |
| SCHEMBL12988943 | 0.78 | EHMT2 (0.49) | ALDH1A1CYP3A4GAA | |
| SCHEMBL7034412 | 0.77 | HTT (0.48) | NPSR1L3MBTL1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |