Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12988943 | 0.85 | EHMT2 (0.49) | EHMT2ALDH1A1GAAHSD17B10EZH2 | |
| SCHEMBL10808825 | 0.84 | GAA (0.47) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL1814668 | 0.81 | FLT3 (0.45) | EHMT2ALDH1A1GAADNMT1POLB | |
| SCHEMBL31203040 | 0.81 | FLT3 (0.45) | EHMT2ALDH1A1GAADNMT1POLB | |
| SCHEMBL29972689 | 0.80 | POLB (0.44) | EHMT2ALDH1A1GAAPOLB | |
| SCHEMBL3023350 | 0.80 | POLB (0.44) | EHMT2ALDH1A1GAAPOLB | |
| SCHEMBL13459865 | 0.79 | DRD2 (0.46) | QDPR | |
| SCHEMBL5257134 | 0.79 | QDPR (0.44) | GAAQDPRNSD2 | |
| SCHEMBL10035929 | 0.78 | NPSR1 (0.56) | ALDH1A1GAACYP3A4 | |
| SCHEMBL282999 | 0.77 | QDPR (0.52) | EHMT2GAAQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |