Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15513239 | 0.81 | NAMPT (0.43) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL15513241 | 0.81 | NAMPT (0.43) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL14810722 | 0.80 | QDPR (0.58) | SLC6A4LMNARAB9AQDPR | |
| SCHEMBL15502395 | 0.79 | MAPT (0.39) | SLC6A4MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL13490629 | 0.78 | CCR1 (0.48) | SLC6A4WNT3AQDPR | |
| SCHEMBL595687 | 0.77 | GRM1 (0.52) | MAPTALDH1A1LMNAWNT3A | |
| SCHEMBL29977228 | 0.77 | GRM1 (0.52) | MAPTALDH1A1LMNAWNT3A | |
| SCHEMBL13490635 | 0.76 | QDPR (0.45) | WNT3AQDPR | |
| SCHEMBL21038282 | 0.76 | SLC6A4 (0.46) | SLC6A4WNT3AQDPR | |
| SCHEMBL20160629 | 0.76 | SLC6A4 (0.46) | SLC6A4WNT3AQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |