Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036423 | 0.90 | BRD4 (0.45) | BRD4FAAHCREBBPADORA1 | |
| SCHEMBL9954382 | 0.88 | NPBWR1 (0.44) | NPBWR1ITGB1ITGA4ITGB7FAAH | |
| SCHEMBL9953640 | 0.85 | NPBWR1 (0.41) | NPBWR1ITGB1ITGA4ITGB7CREBBP | |
| SCHEMBL10036424 | 0.85 | NPBWR1 (0.40) | NPBWR1FAAH | |
| SCHEMBL15305627 | 0.80 | PTGS2 (0.48) | FAAHCREBBP | |
| SCHEMBL9953587 | 0.78 | PPARG (0.41) | NPBWR1FAAHMCHR1 | |
| SCHEMBL16588906 | 0.76 | USP2 (0.40) | NPBWR1ITGB1ITGA4ITGB7CREBBP | |
| SCHEMBL16735445 | 0.76 | NPBWR1 (0.45) | NPBWR1ITGB1ITGA4ITGB7FAAH | |
| SCHEMBL16735444 | 0.75 | NPBWR1 (0.46) | NPBWR1ITGB1ITGA4ITGB7 | |
| SCHEMBL9954116 | 0.75 | PTGS2 (0.43) | ITGB1ITGA4ITGB7CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085001-A1 | DIARYLPYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF FOR THE TREATMENT OF HUMANS | PIERRE FABRE MEDICAMENT (FR) | 2012-06-28 | — | — | WO | disclosed |