SCHEMBL10035982

SCHEMBL10035982

CN(C)c1ccc(/C=C/C2=[N+](C)c3ccccc3C2(C)C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.62
APP P05067 7/20 0.62
VDR P11473 4/20 0.50
RELA Q04206 1/20 0.50
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
LMNA P02545 5/20 0.48
HTT P42858 4/20 0.48
MMP14 P50281 1/20 0.48
THRB P10828 4/20 0.47
ALDH1A1 P00352 3/20 0.47
RECQL P46063 3/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
INSR P06213 1/20 0.46
NPSR1 Q6W5P4 3/20 0.45
ALPG P10696 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
GFER P55789 1/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13245094 1.00 MAPT (0.62) MAPTAPPVDRRELAMEN1
Iodide SCHEMBL7758713 0.99 MAPT (0.62) MAPTAPPVDRRELAMEN1
Iodide SCHEMBL7758714 0.99 MAPT (0.62) MAPTAPPVDRRELAMEN1
SCHEMBL1405400 0.92 APP (0.53) MAPTAPPVDRRELAMEN1
SCHEMBL1405401 0.92 APP (0.53) MAPTAPPVDRRELAMEN1
SCHEMBL25664248 0.90 MAPT (0.72) MAPTAPPVDRRELAMEN1
SCHEMBL6128356 0.88 MAPT (0.60) MAPTAPPVDRRELAMEN1
Perchlorate SCHEMBL1532818 0.87 KMT2A (0.54) MAPTAPPVDRRELAMEN1
Perchlorate SCHEMBL1532815 0.87 KMT2A (0.54) MAPTAPPVDRRELAMEN1
Perchlorate SCHEMBL29959735 0.87 KMT2A (0.54) MAPTAPPVDRRELAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9730876-B2 Process for dyeing keratin fibres comprising a dye-pigment, a photoactive compound and a light source L'OREAL (FR) 2017-08-15 US disclosed
US-20150224041-A1 PROCESS FOR DYEING KERATIN FIBRES COMPRISING A DYE-PIGMENT, A PHOTOACTIVE COMPOUND AND A LIGHT SOURCE L'OREAL (FR) 2015-08-13 US disclosed
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-02-09 US disclosed
US-7754863-B2 Metal complex compounds for the optical recording, storage and playback of information; satisfactory sensitivity and recording properties, especially at high recording speeds CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-13 US disclosed
US-20070248782-A1 High-Capacity Optical Storage Media CIBA SPECIALTY CHEMICALS CORP. 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224041-A1 PROCESS FOR DYEING KERATIN FIBRES COMPRISING A DYE-PIGMENT, A PHOTOACTIVE COMPOUND AND A LIGHT SOURCE KRT18, IK, CUTA MAPT 236/4885APP 335/4885VDR 2295/4885
US-20120035187-A1 ANTI-NEURODEGENERATIVE DISEASE AGENT SNCA, PSEN1, CDR2 MAPT 43/4885APP 15/4885VDR 3185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.