⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782168 | 1.00 | CXCR4 (0.41) | — | |
| SCHEMBL674050 | 0.94 | CXCR4 (0.53) | — | |
| SCHEMBL235202 | 0.93 | — | — | |
| SCHEMBL175198 | 0.90 | — | — | |
| SCHEMBL600790 | 0.90 | CXCR4 (0.53) | — | |
| SCHEMBL566326 | 0.88 | ALDH1A1 (0.53) | — | |
| SCHEMBL1779850 | 0.87 | CXCR4 (0.50) | — | |
| SCHEMBL1782490 | 0.86 | HIF1A (0.42) | — | |
| SCHEMBL1640 | 0.86 | — | — | |
| SCHEMBL675729 | 0.85 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 33850 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359584-A | Dihydropyrazoles and their use | 中国药科大学 | 2024-07-19 | — | — | CN | claimed |
| EP-4140989-B1 | 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HEXAPHARMATEC CO LTD (KR) | 2024-07-17 | — | — | EP | claimed |
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | claimed |
| EP-3816164-B9 | ISOTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND AS IRAK4 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2024-07-10 | — | — | EP | claimed |
| CN-118302423-A | Amine compound and use thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-07-05 | — | — | CN | claimed |
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| WO-2024138018-A1 | TREATMENT OF GEMIN5-MEDIATED DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-06-27 | — | — | WO | claimed |
| WO-2024131265-A1 | COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2024-06-27 | — | — | WO | claimed |
| EP-4389130-A1 | APPLICATION OF STEROID COMPOUND IN PREPARATION OF DRUG FOR PREVENTING AND/OR TREATING EYE FLOATERS | Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd. (CN) | 2024-06-26 | — | — | EP | claimed |
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | claimed |
| EP-0047005-A1 | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-03-10 | — | — | EP | claimed |
| US-4317823-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-02 | — | — | US | claimed |
| US-4311700-A | ANTIULCER, GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-01-19 | — | — | US | claimed |
| US-4302453-A | Antiarrhythmic tetrahydronaphthalene derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-11-24 | — | — | US | claimed |
| EP-0028940-A1 | Antiarrhythmic tetrahydronaphthalene derivatives | E.R. Squibb & Sons, Inc. (US) | 1981-05-20 | — | — | EP | claimed |
| US-4171361-A | HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4110319-A | NATURAL RUBBER OR DIENE POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-08-29 | — | — | US | claimed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | claimed |
| US-3988467-A | Aminoacyl compounds | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | claimed |
| US-3953469-A | TRANQUILLIZERS | E. R. SQUIBB & SONS, INC. (US) | 1976-04-27 | — | — | US | claimed |