SCHEMBL674050

SCHEMBL674050

C1C[N]CCNCCCNCCNC1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 1/20 0.37
HIF1A Q16665 1/20 0.35
MAPT P10636 1/20 0.35
PDE4A P27815 1/20 0.35
KDR P35968 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782168 0.94 CXCR4 (0.41) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL10036 0.94
SCHEMBL600790 0.91 CXCR4 (0.53) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL1779850 0.88 CXCR4 (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL235202 0.87
SCHEMBL675729 0.86 ALDH1A1 (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL175198 0.85
SCHEMBL567629 0.84
SCHEMBL1781454 0.84 HIF1A (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL1782381 0.84 HIF1A (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203336-A1 Paints Containing Driers Based on Vanadium Compounds Bearing Anions of Sulfonic Acids as Counter Ions BORCHERS GMBH (DE) 2023-06-29 US claimed
WO-2023052294-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE USING LEWIS ACIDS BORCHERS GMBH (DE) 2023-04-06 WO claimed
EP-3024898-B1 ENCAPSULATED CATALYSTS OMG UK TECH LTD (GB) 2017-11-08 EP claimed
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-20160145464-A1 ENCAPSULATED CATALYSTS OMG UK TECHNOLOGY LIMITED (GB) 2016-05-26 US claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
EP-1095031-B1 ANTIVIRAL MACROCYCLIC COMPOUNDS GENZYME CORP (US) 2013-08-21 EP claimed
EP-0747368-B1 Derivatives of monocyclic polyamines, their preparation, and their use as antiviral agents ANORMED INC (CA) 2007-04-25 EP claimed
US-7160872-B2 Methods to treat conditions mediated by chemokine receptors ANORMED INC. (CA) 2007-01-09 US claimed
US-20040235814-A1 Methods to treat conditions mediated by chemokine receptors GENZYME CORPORATION 2004-11-25 US claimed
US-20030018189-A1 Cyclic polyamines having total 9-24 members which have activity in against HIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors GENZYME CORPORATION 2003-01-23 US claimed
EP-1095031-A1 ANTIVIRAL MACROCYCLIC COMPOUNDS ANORMED INC. (CA) 2001-05-02 EP claimed
WO-2000002870-A1 ANTIVIRAL MACROCYCLIC COMPOUNDS ANORMED INC. (CA) 2000-01-20 WO claimed
JP-9012560-A None JP disclosed
US-20230203336-A1 Paints Containing Driers Based on Vanadium Compounds Bearing Anions of Sulfonic Acids as Counter Ions BORCHERS GMBH (DE) 2023-06-29 US disclosed
WO-2023052294-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE USING LEWIS ACIDS BORCHERS GMBH (DE) 2023-04-06 WO disclosed
WO-2001016270-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2001-03-08 WO disclosed
WO-2001016272-A2 LIGAND AND COMPLEX FOR CATALYTICALLY BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2001-03-08 WO disclosed
US-5817807-A CONTAINING A 1,4,8,11-TETRAAZACYCLOTETRADECANE RING ANORMED INC. (CA) 1998-10-06 US disclosed
JP-H0912560-A IMPROVED ANTIVIRAL COMPOUND JOHNSON MATTHEY PLC 1997-01-14 JP disclosed