Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036414 | 0.82 | DPP3 (0.58) | DPP3CAPN1CTSBTACR1KISS1R | |
| SCHEMBL24245857 | 0.81 | DPP3 (0.54) | DPP3CAPN1CTSBTACR1GHSR | |
| SCHEMBL13018973 | 0.79 | DPP3 (0.55) | DPP3CAPN1CTSBKISS1RNTSR2 | |
| SCHEMBL13950953 | 0.79 | DPP3 (0.55) | DPP3CAPN1CTSBKISS1RNTSR2 | |
| SCHEMBL22753494 | 0.78 | DPP3 (0.51) | DPP3CAPN1CTSBGHSRBCL2A1 | |
| SCHEMBL29540462 | 0.74 | CAPN1 (0.50) | DPP3CAPN1CTSBTACR1KISS1R | |
| SCHEMBL10036419 | 0.74 | DPP3 (0.60) | DPP3CAPN1CTSBTACR1KISS1R | |
| SCHEMBL13226652 | 0.73 | CAPN1 (0.54) | DPP3CAPN1CTSBTACR1KISS1R | |
| SCHEMBL13380048 | 0.73 | DPP3 (0.55) | DPP3CAPN1CTSBTACR1 | |
| SCHEMBL13393768 | 0.73 | MC4R (0.53) | DPP3CAPN1CTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271665-B1 | HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS | SANOFI SA (FR) | 2012-01-18 | — | — | EP | disclosed |