Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 10/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018973 | 1.00 | DPP3 (0.55) | DPP3CAPN1CTSBCCKBRNTSR2 | |
| SCHEMBL13928247 | 0.91 | DPP3 (0.46) | DPP3CAPN1CTSBCCKBRNTSR2 | |
| SCHEMBL13950905 | 0.91 | DPP3 (0.46) | DPP3CAPN1CTSBCCKBRNTSR2 | |
| SCHEMBL24245857 | 0.86 | DPP3 (0.54) | DPP3CAPN1CTSB | |
| SCHEMBL10036414 | 0.82 | DPP3 (0.58) | DPP3CAPN1CTSBCCKBRKISS1R | |
| SCHEMBL22753494 | 0.82 | DPP3 (0.51) | DPP3CAPN1CTSBCCKBR | |
| SCHEMBL30310982 | 0.81 | CCKBR (0.61) | DPP3CCKBR | |
| SCHEMBL12914540 | 0.80 | SLC6A2 (0.54) | NTSR2NTSR1SORT1 | |
| SCHEMBL646710 | 0.80 | SLC6A2 (0.54) | NTSR2NTSR1SORT1 | |
| SCHEMBL30310882 | 0.80 | CCKBR (0.61) | DPP3CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048226-A1 | Inhibitors of caspases | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048226-A1 | Inhibitors of caspases | CASP1, APAF1, IRF3 | DPP3 405/4885CAPN1 208/4885CTSB 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.