SCHEMBL10036414

SCHEMBL10036414

C/C=C(\NC(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(C)=O)C(C)C)C(=O)NC

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.58
▸ CAPN1 P07384 2/20 0.49
▸ CTSB P07858 2/20 0.49
▸ KISS1R Q969F8 3/20 0.49
▸ CCKBR P32239 6/20 0.48
▸ TACR1 P25103 1/20 0.48
▸ REN P00797 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036419 0.92 DPP3 (0.60) DPP3CAPN1CTSBKISS1RTACR1
SCHEMBL13018973 0.82 DPP3 (0.55) DPP3CAPN1CTSBKISS1RCCKBR
SCHEMBL13950953 0.82 DPP3 (0.55) DPP3CAPN1CTSBKISS1RCCKBR
SCHEMBL24245857 0.82 DPP3 (0.54) DPP3CAPN1CTSBTACR1
SCHEMBL10036420 0.82 DPP3 (0.48) DPP3CAPN1CTSBKISS1RTACR1
SCHEMBL29572021 0.81 DPP3 (0.71) DPP3TACR1REN
SCHEMBL22753494 0.79 DPP3 (0.51) DPP3CAPN1CTSBCCKBR
SCHEMBL30610091 0.78 DPP3 (0.69) DPP3
SCHEMBL29648960 0.78 DPP3 (0.69) DPP3
SCHEMBL29993706 0.77 DPP3 (0.68) DPP3REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2271665-B1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS SANOFI SA (FR) 2012-01-18 — — EP disclosed
US-20110144001-A1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS SANOFI-AVENTIS (FR) 2011-06-16 — — US disclosed
US-20110144001-A1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS SANOFI-AVENTIS (FR) 2011-06-16 — — US disclosed
WO-2009121483-A1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS SANOFI-AVENTIS (FR) 2009-10-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144001-A1 HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS HM13, VIP, NPBWR1 DPP3 1697/4885CAPN1 2286/4885CTSB 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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