Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | MYC | P01106 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443977 | 0.81 | MEN1 (1.00) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL8788860 | 0.80 | MEN1 (0.67) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL300144 | 0.78 | MEN1 (0.67) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL9698164 | 0.77 | MAPT (0.63) | MIFMEN1KMT2APOLBMAPT | |
| SCHEMBL17781757 | 0.77 | MEN1 (0.67) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL25343177 | 0.76 | MEN1 (0.77) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL12818156 | 0.76 | GSTM2 (0.70) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL19387685 | 0.75 | GSTM2 (0.68) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL21239902 | 0.75 | GSTM2 (0.68) | MIFMEN1KMT2AUSP2HTT | |
| SCHEMBL8429536 | 0.75 | GSTM2 (0.68) | MIFMEN1KMT2AUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |