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Sugi Predict / Targets / GSTM2

GSTM2

Glutathione S-transferase Mu 2 · P28161 · GSTM2 on Sugi Atlas →

3,729 patent compounds predicted against GSTM2, 1,937 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL300204 SCHEMBL300204 0.82 20/20
SCHEMBL3712753 SCHEMBL3712753 0.65 20/20
SCHEMBL6049348 SCHEMBL6049348 0.74 19/20
SCHEMBL3502370 SCHEMBL3502370 0.74 19/20
SCHEMBL761344 SCHEMBL761344 1.00 18/20
SCHEMBL6049336 SCHEMBL6049336 1.00 18/20
SCHEMBL6056044 SCHEMBL6056044 1.00 18/20
SCHEMBL6056085 SCHEMBL6056085 0.64 18/20
SCHEMBL296538 SCHEMBL296538 0.58 18/20
SCHEMBL296539 SCHEMBL296539 0.58 18/20
SCHEMBL296944 SCHEMBL296944 0.77 17/20
SCHEMBL301085 SCHEMBL301085 0.57 17/20
SCHEMBL5713923 SCHEMBL5713923 0.50 17/20
SCHEMBL297913 SCHEMBL297913 1.00 16/20
SCHEMBL6049433 SCHEMBL6049433 0.75 16/20
SCHEMBL298137 SCHEMBL298137 0.72 16/20
SCHEMBL3500242 SCHEMBL3500242 0.70 16/20
SCHEMBL3063567 SCHEMBL3063567 0.47 16/20
SCHEMBL6833698 SCHEMBL6833698 0.77 15/20
SCHEMBL297980 SCHEMBL297980 0.75 15/20

Clinical trials — most relevant to GSTM2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma PHASE3COMPLETED
Cysteine Supplementation in Critically Ill Neonates PHASE2/PHASE3UNKNOWN
Paracetamol Toxicity in Septic Patients PHASE3SUSPENDED
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS PHASE1/PHASE2COMPLETED
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure PHASE2COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy PHASE2RECRUITING
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers PHASE2RECRUITING
Prevent Cardiac Surgery Associated AKI Trial PHASE2RECRUITING
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism PHASE2ACTIVE_NOT_RECRUITING
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD PHASE2COMPLETED
Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria PHASE1/PHASE2SUSPENDED
A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) PHASE1UNKNOWN
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer PHASE1COMPLETED
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis PHASE1COMPLETED
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE) nanCOMPLETED
Broccoli and Vascular Health Study nanCOMPLETED
Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer nanCOMPLETED
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma nanCOMPLETED
Cancer and Hearing Loss Related in Children nanCOMPLETED
Genes Influencing Iron Overload State nanCOMPLETED
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers nanCOMPLETED
Mechanisms of Response to Diesel Exhaust in Subjects With Asthma nanWITHDRAWN
The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease nanCOMPLETED
Markers of Oxidative Stress Diastolic Dysfunction nanUNKNOWN
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans nanCOMPLETED
Factors in Childhood Lung Susceptibility to Pollution nanCOMPLETED
Gene-Environment Interactions in Rheumatoid Arthritis Autoimmunity Disease Severity nanCOMPLETED
Genetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain Tumor nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GSTM2 binder may also engage these)

ProteinNameSimilarity
Q9TSM4 — 1.000 Q9TSM4 →
Q9BEB0 — 1.000 Q9BEB0 →
Q9TSM5 — 1.000 Q9TSM5 →
P48774 — 1.000 P48774 →
Q03013 — 1.000 Q03013 →
Q9BEA9 — 1.000 Q9BEA9 →
P08010 — 1.000 P08010 →
P30116 — 1.000 P30116 →
P21266 — 1.000 P21266 →
P46409 — 1.000 P46409 →
P19639 — 1.000 P19639 →
Q9N0V4 — 1.000 Q9N0V4 →
P15626 — 1.000 P15626 →
P08009 — 0.999 P08009 →
P10649 — 0.999 P10649 →
GSTM1 Glutathione S-transferase Mu 1 0.999 landscape →
P04905 — 0.998 P04905 →
P31671 — 0.998 P31671 →
O35660 — 0.998 O35660 →
Q5R8E8 — 0.998 Q5R8E8 →
Q80W21 — 0.997 Q80W21 →
P46439 — 0.996 P46439 →
Q9Z1B2 — 0.996 Q9Z1B2 →
Q00285 — 0.996 Q00285 →
P20136 — 0.996 P20136 →
P46419 — 0.995 P46419 →
Q8R5I6 — 0.994 Q8R5I6 →
Q5BK56 — 0.994 Q5BK56 →
P30112 — 0.994 P30112 →
P16413 — 0.993 P16413 →