SCHEMBL443977

SCHEMBL443977

O=[N+]([O-])c1ccc(NCc2ccccc2)c2nonc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
USP2 O75604 1/20 1.00
HTT P42858 1/20 1.00
RECQL P46063 1/20 1.00
MIF P14174 1/20 0.67
MYC P01106 6/20 0.65
IDO1 P14902 4/20 0.65
GSTM2 P28161 5/20 0.58
GSTP1 P09211 4/20 0.57
POLB P06746 1/20 0.57
GAA P10253 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25343177 0.87 MEN1 (0.77) MEN1KMT2AUSP2HTTRECQL
SCHEMBL611015 0.84 KMT2A (0.72) MEN1KMT2AUSP2HTTRECQL
SCHEMBL10036668 0.81 MIF (1.00) MEN1KMT2AUSP2HTTRECQL
SCHEMBL300144 0.81 MEN1 (0.67) MEN1KMT2AUSP2HTTRECQL
SCHEMBL17781757 0.80 MEN1 (0.67) MEN1KMT2AUSP2HTTRECQL
SCHEMBL8788860 0.80 MEN1 (0.67) MEN1KMT2AUSP2HTTRECQL
SCHEMBL17927380 0.80 MEN1 (0.65) MEN1KMT2AUSP2HTTRECQL
SCHEMBL10824789 0.80 MEN1 (0.66) MEN1KMT2AUSP2HTTRECQL
SCHEMBL286617 0.79 POLB (0.69) MEN1KMT2AUSP2HTTRECQL
SCHEMBL12818156 0.79 GSTM2 (0.70) MEN1KMT2AUSP2HTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998021-B1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF PROVOST FELLOWS FOUND SCHOLARS & OTHER MEMBERS BOARD COLLEGE HOLY & UND (IE) 2026-03-11 EP claimed
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) 2026-02-19 US claimed
US-12180378-B2 Colorimetric sensor formulation and use thereof THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) 2024-12-31 US claimed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 US claimed
EP-3998021-A1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, (IE) 2022-05-18 EP claimed
EP-3846692-B1 A METHOD FOR DETERMINING THE OXYGEN CONTENT OF AN ATMOSPHERE THE PROVOST FELLOWS FOUND SCHOLARS AND THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIV (IE) 2022-03-02 EP claimed
US-20210292353-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-09-23 US claimed
US-20210246326-A1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) 2021-08-12 US claimed
EP-3829565-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2021-06-09 EP claimed
EP-3616612-A1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth, (IE) 2020-03-04 EP claimed
WO-2015144282-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2015-10-01 WO claimed
EP-2850091-A1 METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS President and Fellows of Harvard College (US) 2015-03-25 EP claimed
US-20150079618-A1 METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-03-19 US claimed
CN-103694268-A Kinase activity probe and method for treating related diseases LI XITAO 2014-04-02 CN claimed
WO-2013151697-A1 METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-10-10 WO claimed
US-8480928-B2 Inorganic-organic composite luminophore KARLSRUHER INSTITUT FUR TECHNOLOGIE (KIT) (DE) 2013-07-09 US claimed
US-20110198538-A1 INORGANIC-ORGANIC COMPOSITE LUMINOPHORE Karlsruher Institut for Technologie (KIT) (DE) 2011-08-18 US claimed
EP-2179006-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE Karlsruher Institut für Technologie (DE) 2010-04-28 EP claimed
WO-2009100800-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE UNIVERSITÄT KARLSRUHE (TH) (DE) 2009-08-20 WO claimed
US-20020045679-A1 Aqueous ink composition HITACHI MAXELL, LTD. (JP) 2002-04-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES GOT1, RNMT, GNAO1 MEN1 2505/4885KMT2A 2458/4885USP2 4319/4885
US-20150079618-A1 METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS MAGT1, GALNT1, NMT1 MEN1 2319/4885KMT2A 1399/4885USP2 3211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.