SCHEMBL1003680

SCHEMBL1003680

CCCCCNC(=O)c1ccccc1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.96
L3MBTL1 Q9Y468 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.69
HDAC3 O15379 7/20 0.67
HDAC1 Q13547 4/20 0.67
HDAC2 Q92769 4/20 0.67
HDAC4 P56524 3/20 0.67
HDAC7 Q8WUI4 3/20 0.67
HDAC10 Q969S8 3/20 0.67
HDAC11 Q96DB2 3/20 0.67
HDAC8 Q9BY41 3/20 0.67
HDAC6 Q9UBN7 3/20 0.67
HDAC9 Q9UKV0 3/20 0.67
HDAC5 Q9UQL6 3/20 0.67
DRD2 P14416 1/20 0.65
DRD4 P21917 1/20 0.65
DRD3 P35462 1/20 0.65
NPC1 O15118 1/20 0.64
RAB9A P51151 1/20 0.64
TSHR P16473 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927370 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL20216434 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL1002638 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL1003239 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL8204741 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
Hydrochloric Acid SCHEMBL11612942 0.98 NAAA (0.93) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL1004555 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL1002305 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL421014 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1
SCHEMBL29280581 0.98 NAAA (1.00) NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229483-A Amide potassium complex for catalyzing lactide ring-opening polymerization and preparation method thereof 北京服装学院 2023-12-15 CN claimed
CN-112107684-A Methods and compositions for treating ARID2 or HSPA1A mediated diseases 中国科学院分子细胞科学卓越创新中心 2020-12-22 CN claimed
CN-108864038-A 3- amide groups-N- aryl benzamides class compound and preparation and application 浙江大学 2018-11-23 CN claimed
CN-102762557-B Triazolopyridine BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-07 CN claimed
CN-102762557-A Triazolopyridines BAYER SCHERING PHARMA AG 2012-10-31 CN claimed
EP-1888595-A2 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2008-02-20 EP claimed
WO-2006110917-A2 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2006-10-19 WO claimed
US-6037311-A PLANT PROTECTION COMPOSITIONS BASED ON BENZAMIDE COMPOUND(S) AND CYCLODEXTRIN(S) ROQUETTE FRERES (FR) 2000-03-14 US claimed
EP-0934264-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (US) 1999-08-11 EP claimed
WO-1998012177-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (JP) 1998-03-26 WO claimed
CN-1037510-C Indole derivatives HOFFMANN LA ROCHE (CH) 1998-02-25 CN claimed
EP-0542973-B1 PHYTOSANITARY COMPOSITION, METHOD OF PREPARING THE SAME AND USE THEREOF ESPECIALLY FOR COMBATTING WEEDS ROQUETTE FRERES (FR) 1996-01-17 EP claimed
CN-1088576-A Indole derivatives HOFFMANN LA ROCHE (CH) 1994-06-29 CN claimed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP claimed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP claimed
US-12415822-B2 Small molecule inhibitors selective for polo-like kinase protein UNIVERSITY OF SOUTH CAROLINA (US) 2025-09-16 US disclosed
US-20250188201-A1 CATALYST FOR PHOTOCATALYTIC POLYMERIZATION REACTION, AND APPLICATION THEREOF BEIJING INSTITUTE OF FASHION TECHNOLOGY (CN) 2025-06-12 US disclosed
US-4303664-A Novel penicillin derivatives containing a coumarin nucleus and medicines containing the same TEIJIN LIMITED (JP) 1981-12-01 US disclosed
US-4195090-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4115575-A CARDIOVASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415822-B2 Small molecule inhibitors selective for polo-like kinase protein PLK2, PLK4, PLK3 NAAA 2570/4885L3MBTL1 1136/4885SMN1; SMN2 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.